FROM Washington D.C.
Just take Rt 50 towards Annapolis and then the Davidsonville RT. 424 exit South... It's about 30 minutes from there... Or the alternative route (the Back Door as we call it) is to come out the Suitland Parkway past Andrews Air Force Base on Rt. 4 and take the Deale exit... Either way is about 55 minutes from downtown Washington D.C. with non-rush hour traffic.
From BALTIMORE, PHiladelphia AND NEW YORK
From Baltimore, a take I 695 to I 97 South and then Rt. 50 West to Annapolis and Rt 2 South. If coming from Philadelphia, New York or points north, take I-95 South and then the Harbor Tunnel under the Chesapeake Bay, to I-97 South, then Rt. 50 West to Annapolis and Rt 2 South
FROM RICHMOND and PoINTS SOUTH
Depending on the traffic, you can take i-95 North towards Washington D.C. and then the Capitol Beltway (I-495 West) to the Rt 4 Exit at Pennsylvania Ave and then out the Suitland Parkway past Andrews Air Force Base. Alternatively, to avoid Northern Virginia, Washington D.C. traffic, once you pass Richmond, Rt. 207 and Rt. 301 through some very scenic country, including Amish communities.